Black Box Warnings: Prescribing Potentially Dangerous Medications Safely – Bob McMullen

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Exploring the Essential Features of “Black Box Warnings: Prescribing Potentially Dangerous Medications Safely – Bob McMullen”

Who among us does not prescribe (or have patients taking) antidepressants, diabetic medications or fluoroquinolones? Many commonly prescribed medications contain safety warnings from the FDA, called “Black Box Warnings.” It is easy to forget the warnings on relatively common drugs, and even easier to forget the warnings for less commonly used medications. This presentation will be interactive and fun while Bob McMullen, EdD, PA-C reviews the dangers of many medications, to ensure you are safely prescribing for patients. 

Speaker:

Bob McMullen, EdD, PA-C, is a physician assistant with more than 30 years of experience in primary care and emergency medicine. He is a respected and sought-after presenter, teaching experienced clinicians on numerous topics, including pharmacology, for the past 20 years. His passions include making complex topics simple and accessible. As a provider and educator, pharmacology and safe prescribing is an on-going area of interest, particularly how mechanisms of action and pharmacokinetics affect drug-drug interactions.

Speaker Disclosures:
Financial: Bob McMullen has employment relationships with Silver Healthcare, A.T. Still University, and ATSU. He receives a speaking honorarium from PESI, Inc. He has no relevant financial relationships with ineligible organizations.
Non-financial: Bob McMullen is a member of the American Academy of Physician Assistants, the Physician Assistant Education Association, and the Society of Point of Care Ultrasound.

Objectives:

1. Distinguish the black box warnings for common medications. 
2. Analyze complications listed as Black Box Warnings, such as QT prolongation, increased suicidality, increased heart disease…and more! 
3. Evaluate the dangers of less commonly prescribed medications. 
4. Determine opportunities to improve prescriptive safety within your own practice.

Outline:

Dangerous Medication Considerations for the Heart  

• NSAIDs 
• Promotility drugs 
• Combination oral contraceptives 
• Thiazolidinediones 
• Beta blockers 

Dangerous Medication Considerations for Pediatric Patients 

• Antibiotics (doxycycline, tigecycline) 
• Opioids 
• Birth control 
• Acne meds 
• RAAS drugs  
• Misoprostol 

Dangerous Medication Considerations for Breathing  

• Opioids 
• Methadone 
• Tramadol 
• Inhaled insulin 
• Nitroprusside 
• LABAs 

Dangerous Medication Considerations for Blood Gasses 

• Metformin 
• Benzocaine-containing sprays or gels  

Dangerous Medication Considerations for Bullae, Blisters, and Biopsies 

• Antiepileptic drugs 
• Topical calcineurin inhibitors 
• Psoralen 
• Antiemetics 

Dangerous Medication Considerations for Bowels 

• IBS drugs 
• NSAIDs 
• APAP 

Dangerous Medication Considerations for Bleeding 

• Platelet inhibitors 
• Thrombin inhibitors 
• Factor Xa inhibitors 
• Anticoagulant, Vitamin K Antagonist 

Dangerous Medication Considerations for the Body 

• Fluoroquinolones 
• Botulinum toxins 

Dangerous Medication Considerations for the Brain 

• Antidepressants 
• Atypical antipsychotics  
• Amphetamine, dextroamphetamine, lisdexamfetamine 
• Metoclopramide

Target Audience:

• Nurses
• Nurse Practitioners
• Pharmacists
• Physicians
• Physician Assistants

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