Eric Wombwell – Pharmacology of Infectious Diseases & Immunizations for Advanced Practice Clinicians – PESI

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Pharmacology of Infectious Diseases & Immunizations for Advanced Practice Clinicians
Speaker: Eric Wombwell, PharmD, BCIDP
Duration: 6 Hours 09 Minutes
Format: Audio and Video

Description

Watch this recording and learn proper prescribing, patient education and monitoring procedures for a variety of drug regimens used to treat common acute and chronic infectious diseases. Choosing an antibacterial agent can be challenging, given the plethora of drugs available on the market and the emerging trend in bacterial resistance.

You will learn the pharmacology of different classes of antimicrobials used to treat infectious disease states encountered in clinical practice. Discover the spectrums of activity, pharmacokinetic characteristics and parameters for monitoring therapeutic outcomes. Emphasis is placed on the new antimicrobials and advances in evidence-based treatment guidelines.

You will leave this recording better prepared to design appropriate and cost-effective drug regimens for improved therapeutic outcomes.

Speaker

Eric Wombwell, PharmD, BCIDP
Dr. Eric Wombwell is a board-certified infectious diseases pharmacist and clinical associate professor for the Department of Pharmacy Practice and Administration at the University of Missouri – Kansas City, School of Pharmacy. Eric completed his PharmD degree at the University of Missouri Kansas City, followed by an ASHP accredited pharmacy practice residency at the Kansas City VA Medical Center. Following residency, he accepted a full-time non-tenured clinical faculty position at the University of Missouri – Kansas City, School of Pharmacy. His teaching responsibilities include infectious diseases topics throughout the curriculum. Eric also has a clinical appointment at Centerpoint Medical Center rounding with the infectious diseases consult team and supporting antimicrobial stewardship efforts at the facility.

Eric is regularly published in pharmacy and infectious diseases research and is frequently invited to deliver continuing education presentations locally and nationally to various health-professional audiences. He is recognized for excellence in teaching through various awards, including the “Missouri Pharmacist Association – UMKC Faculty Member of the Year”, and the “University of Missouri – Kansas City Provost’s Award for Excellence in Teaching”.

Speaker Disclosures:
Financial: Eric Wombwell has an employment relationship with the University of Missouri. He receives a speaking honorarium, recording royalties, and a consulting fee from PESI, Inc. He has no relevant financial relationships with ineligible organizations.
Non-financial: Eric Wombwell is a member of the Society of Infectious Diseases Pharmacists, the Missouri Pharmacists Association, American Association of Colleges of Pharmacy, Infectious Diseases Society of America, and Centerpoint Medical Center.

Outline

Antimicrobials

• Drug classes
• Pharmacokinetic Properties
  • Concentration-dependent killing
  • Time-dependent killing
  • Post-antibiotic effect
• Common interactions with other drugs

Antibacterial Allergies – Sulfa and Penicillin

• Define true allergy
• Sulfonamide antibiotics vs non-antibiotics
• Penicillin – Cephalosporin cross-sensitivity

Bacteria

• Differentiation
• Normal flora
• Common pathogens

Antibacterial Resistance – Contributing Factors

• Trends
• Mechanisms of resistance
• Contributing factors

Methicillin-Resistant Staphylococcus Aureus – Community versus Hospital Acquired

• Differentiating between CA- and HA-MRSA
• Current clinical practice guidelines
• Pharmacologic management

Enterobacteriaceae Resistance

• Extended Spectrum Beta-Lactamase (ESBL)
  • What are ESBLs
  • Pharmacologic management
• Carbapenem-Resistant Enterobacteriaceae (CRE)
  • What are CREs
  • Pharmacologic management

Urinary Tract Infections

• Bacterial Etiology, Signs and Symptoms and Diagnosis
• Cystitis and pyelonephritis
• Complicated and uncomplicated
• UTIs in pregnancy
• Treatment (IDSA Guideline Treatment Algorithm)
  • Acute
  • Recurrent and relapse

Clostridium Difficile Infection

• Risk factors
• Pharmacology management
• Fecal Transplantation
• Probiotics literature review

Community–Acquired Pneumonia

• Bacterial etiology
• Diagnosis
• Typical vs. atypical
• Treatment (IDSA/ATS Guidelines) and monitoring
  • Outpatient vs. inpatient
  • Empiric treatment

Healthcare–Associated Pneumonia

• Bacterial etiology
• Treatment (IDSA/ATS Guidelines)

Upper Respiratory Tract Infections

• Sinusitis and pharyngitis
  • Etiology (Viral vs. Bacterial)
  • Treatment

Skin and Soft Tissue Infections

• Cellulitis
• Bacterial etiology
  • Strep. vs. Staph. vs. MRSA
  • Signs & symptoms
  • Treatment (IDSA Guidelines)

Influenza

• Clinical features
• Diagnosis
• Pharmacology management

Immunizations (Adult)

• Types of Vaccines
• General recommendations
• Contraindications & precautions

Objectives

1. Analyze the major classes of antibiotics and their pharmacokinetic characteristics.
2. Apply current evidenced-based approaches to select appropriate treatment regimens for common infections encountered in clinical practice.
3. Prescribe antimicrobials based on empiric dosing recommendations.
4. Plan goals of therapy and parameters for monitoring therapeutic response to antimicrobials.
5. Recommend specific antimicrobial therapeutic drug monitoring to maximize efficacy and minimize toxicities (e.g., vancomycin and aminoglycosides).
6. Develop preventative strategies to limit antimicrobial resistance.
7. Design patient and caregiver education on the proper use of antimicrobials.

Target Audience

• Nurses
• Advanced Practice Nurses
• Clinical Nurse Specialists
• Pharmacists
• Nurse Practitioners
• Physician Assistants

Reviews

Maryanne C
“Excellent presentation. I learned a great deal regarding appropriate antibiotic choices/treatment.”

Robert N
“I thoroughly enjoyed the course, and the lecturer was excellent and very knowledgeable”

Donna S
“I learned so much. Additionally. the handouts are very useful for future reference.”

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