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Exploring the Essential Features of “Laurie Klipfel – Weight Loss Medications: Evaluate Evidence, Risk & Cost for Prescriptive Decisions – PESI”
Weight Loss Medications: Evaluate Evidence, Risk & Cost for Prescriptive Decisions
Speaker: Laurie Klipfel, RN, MSN, ANP-BC, CDCES, WCC®
Duration: 6 Hours 21 Minutes
Format: Audio and Video
Description
You’ve seen it too….
With the goal of losing weight, patients will try endless efforts and gimmicks. As providers, we have explained the importance of maintaining a healthy weight and lifestyle. These conversations can lead to frustrations, for everyone involved.
Studies show a 5-7% weight loss with behavior changes (a mere 10-15 pounds for a 200-pound person). Often weight loss efforts lead to weight cycling, which carries documented health risks and often leads to higher than initial weights. In the past there have been a lot of assumptions about the cause of weight being more behavioral. Newer evidence supports a more genetic, environmental, and biologic relationship with weight.
However, many healthcare providers continue to recommend behavior changes for weight loss, despite documented research showing not only poor success with those tactics but great harm including weight stigma, decreased utilization or delay in medical care, repeated weight loss and regain/weight cycling, reduced self-esteem/motivation, eating disorders, stress, and depression. All of which have been shown to contribute negatively to overall health.
The seriousness of this situation has led both patients and providers to look at pharmacological interventions to manage weight. These options have significant cost and risk that need to be carefully considered against the potential benefits. You have an incredible opportunity to learn from Laurie Klipfel, RN, MSN, ANP-BC, CDCES, WCC, as she breaks down the very latest evidence supported weight loss medication options.
Speaker
Laurie Klipfel, RN, MSN, ANP-BC, CDCES, WCC®
Touchette Regional Hospital
Laurie Klipfel, RN, MSN, ANP-BC, CDCES, WCC®, has been a Certified Diabetes Care and Education Specialist for over 20 years managing both inpatient and outpatient care for patients with diabetes. She has managed several hospital ADA-recognized diabetes education programs, is a Board-Certified Adult Nurse Practitioner with a specialty in endocrinology, and has a certification in wound care.
Laurie is a member of the American Association of Diabetes Care and Education Specialists and past president of her local chapter. She is a certified insulin pump trainer and has published articles on use of insulin pumps for hospitalized patients. Her practical patient experiences, supported by clinical knowledge, provide a blend of information on how to treat diabetes today.
Speaker Disclosures:
Financial: Laurie Klipfel has employment relationships with the VA-St. Louis and the Diabetes & Endocrinology Specialists, Inc. She receives a speaking honorarium and recording royalties from PESI, Inc. She has no relevant financial relationships with ineligible organizations.
Non-financial: Laurie Klipfel is a member of the St. Louis Nurses in Advanced Practice.
Objectives
- Apply the latest evidence to select current pharmacological options for weight loss in patients.
- Analyze the benefit vs cost and risk of the various weight loss medication options available today.
- Evaluate the effect on weight for medications intended to treat other ailments such as hypertension, diabetes, or depression.
- Determine benefits of focusing on outcomes such as health/longevity, rather than weight.
- Choose therapies that best meet individual needs and provide effective support.
- Investigate how big business can influence standards/recommendations for healthcare providers regarding weight loss options.
- Develop techniques for successful motivational interviewing.
Outline
Current Non-Pharmacological Options
“Healthy” Diets
- Dash diet
- Mediterranean diet
- Paleo
- Atkins
- Keto
- Plant-based diet
- Commercially prepared meals
- Commercial weight loss plans
Activity
- Cardio/aerobic
- Resistance training/anerobic
- Stretch/flexibility
- Precautions
Stress management
Sleep hygiene
Surgical options
Motivational techniques to maintain healthy habits and avoiding fads
Pharmacological Options for Weight Loss
Older Medications Taken Off the Market Due to Complications
- Sibutramine
- Fenfluramine/phentermine “fen-phen”
- Lorcaserin
- Limitations/bias of older recommendations
FDA Approved Medications for Weight Loss (Effectiveness, Dosage, Side Effects, Warnings, Cost)
- Orlistat
- Phentermine/topiramate
- Naltrexone/buproprion
- Liraglultide
- Semaglutide
- Setmelanotide (only approved for 3 rare genetic conditions)
Medications Approved for Short Term Use Only (12 weeks)
- Phentermine
- Benzphetamine
- Diethylpropion
- Phendimetrazine
Medications Used Off Label for Weight Loss
- A drug approved for treating a different medical problem
- Two or more drugs at the same time
- A drug for a longer time period than approved by the FDA
“Food Supplements” Not Under FDA Guidelines
Potential Mechanisms of Action for Future Medications
- Regulating several gut hormones at the same time
- Targeting specific genes that cause obesity
- Allowing people to lose body fat without losing muscle during weight loss
- Changing bacteria in the gut to control weight
Medications Used for Other Conditions that Affect Weight
- Diabetes medications
- Hypertension medications
- Psychiatric medications
Target Audience
- Nurse Practitioners
- Clinical Nurse Specialists
- Nurses
- Physician Assistants
- Pharmacists
- Dietitians
- Certified Diabetes Care and Education Specialists
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