Shelly Denes – Clinical Implications of Inflammation & Autoimmunity in Neurological Diseases

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Speaker:Shelly Denes, PT, C/NDT, CFPS, CGCP

Duration:2 Hours

Format:Audio and Video

Copyright:May 18, 2023  

Media Type:Digital Seminar

Description

When inflammation is commonly addressed by rehab professionals, the presence of systemic inflammation is a very different and unique contributing presentation of no less importance. COVID-19, the rise in autoimmune disorders and a growing link of inflammation in neurological diseases furthers the importance of having a baseline understanding of the physiology of systemic inflammation. You will gain insight of the interplay of inflammation, the immune system, and the autonomic nervous system. Application will emphasize the impact on ROM, stiffness, pain, edema, endurance, fatigue, neuroplasticity and more. We will investigate cytokines in COVID-19 and autoimmunity in neurological diseases, namely multiple sclerosis, Parkinson’s Disease and Guillain-Barre Syndrome.

Speaker

Shelly Denes, PT, C/NDT, CFPS, CGCP, is an expert in fall prevention and neuro-rehab with more than 30 years of experience treating patients with hemiplegia, neurological diseases, neuromuscular disorders, TBI, and SCI. She has a special interest in Long COVID, autoimmunity and the impact of chronic inflammation and sleep deprivation in rehab. She has been involved extensively with neuroprosthetic devices, lower extremity orthotics, and exoskeleton devices at the Rehab Institute of Michigan. Mrs. Denes travels nationally to present seminars on fall prevention, Long COVID and geriatric rehabilitation. Additionally, her expertise has been presented through expert witness work and consulting both nationally and locally. She also sits on the State of Michigan Fall Prevention Coalition committee. Shelly Denes is a graduate of University of Michigan’s PT program, and she earned her certification in Neurodevelopmental Treatment for Adult Hemiplegia (NDT) at the Rehab Institute of Chicago. She helped create the certifications for ‘Fall Prevention Specialist’ and ‘Geriatric Care Professional’ with Evergreen Certifications, holds these two certifications and sits on their advisory board.

Speaker Disclosures:

Financial: Michel Janet (Shelly) Denes is the owner of Denes Physical Therapy Consulting LLC. She is a consultant with Experts in Therapy LLC and previously with NewGait™. She receives a speaking honorarium from Motivations, Inc. Michel Janet (Shelly) Denes receives a speaking honorarium and recording royalties from PESI, Inc. She has no relevant financial relationships with ineligible organizations.

Non-financial: Michel Janet (Shelly) Denes is an advisory board member for Evergreen Certifications.

Objectives

1. Investigate cytokines and their impact on inflammation and the immune response in adults.
2. Analyze the cytokine storm and POTS as it relates to COVID-19 and the immune system.
3. Investigate the presence of autoimmunity in neurological diseases and develop interventions for improving function, mobility and return to occupational tasks.
4. Appraise the response of the autoimmune nervous system to chronic inflammation and utilize findings to structure rehab interventions for superior outcomes.

Outline

Cytokines, Inflammation and the Immune System

• What rehab professionals need to know for improved outcomes
• The impact of diagnoses commonly seen in the rehab setting
• Acute vs chronic presentation and implications

The Immune System in COVID-19

• Cytokine Storm
• POTS
• POST-EXERTIONAL Malaise
• Dysautonomia

Auto-Immunity in Neurological Diseases & Treatment

• Multiple Sclerosis
• Parkinson’s Disease
• Guillain-Barre Syndrome

The Link Between Autoimmune Disease and Women

• The impact of hormones
• Increased incidence in women vs men
• Female vs male response to COVID-19
• Influence of testosterone on the immune system
• Stronger immune response may indicate a greater propensity to develop autoimmune disease

Implications for Rehab

• Autonomic Nervous System Regulation
• Identifying Triggers
• Strengthening and Calming the Vagus Nerve – resetting the autonomic nervous system
• Addressing stress and anxiety
• How to Address Sleep deprivation
• Nutrition
• Musculoskeletal factors
• Decreased ROM
• Pain, stiffness, edema
• Treatment considerations: endurance & fatigue
• Utilizing Neuroplasticity

Target Audience

• Nurses
• Nurse Practitioners
• Physical Therapists
• Occupational Therapists

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